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Nigeria: LuxOR study to improve diagnosis of Lassa fever

On Wednesday, June 11, 2025

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As part of a field validation study carried out in Abakaliki, Nigeria, the Luxembourg Opperation Research Unit (LuxOR) evaluated the ReLASV Pan-Lassa rapid diagnostic test (RDT) against the molecular PCR test for the diagnosis of Lassa fever. 

The LuxOR study revealed that the RDT could only detect 4-10% of cases with certainty, making it unsuitable for use in current conditions.

MSF’s Chime Chinda, labelling Lassa fever sample containers for laboratory analysis.
Lassa Fever Detection: Recent Findings Show Rapid Diagnostic Test Falls Short in Abakaliki, Nigeria
Field Evaluation of PanLassa Rapid Test coordinated by LuxOR Shows Inadequate Sensitivity and User-Friendliness for Lassa Fever in Real-World Conditions.

Dr. Temmy Sunyoto, Senior Operational Research Advisor:

MSF’s presence in Abakaliki has given us the opportunity to close critical knowledge gaps around Lassa fever. Because the disease still lacks dependable diagnostics, treatments, and vaccines, we have focused on strengthening existing capacity through rigorous operational research. Over the years, we have worked to reinforce that capacity through several key studies supported by LuxOR.  

We completed the first field validation of a novel rapid diagnostic test, are now finalising a study on predictors of mortality, and have examined risk perception of Lassa fever among both health-care workers and the wider community. These milestones are the direct fruits of our robust partnership with AE-FUTHA and other committed collaborators. 

Generating solid evidence is indispensable to controlling Lassa fever, and operational research will remain a cornerstone of that mission. Together, we are turning science into better care—and a safer future for those most at risk.”

 

‘We are no longer afraid’: MSF hands over Lassa fever care in Ebonyi State

After seven years of critical support from Médecins Sans Frontières (MSF), local health authorities in Ebonyi State are now well equipped to take on Lassa fever with improved infrastructure, training, and resilience—saving lives and restoring confidence in the healthcare system.

Chima Chinda, 32 ans, scientifique de laboratoire de MSF, travaille sur un échantillon de sang d'un cas suspect de fièvre de Lassa à l'unité de virologie du Federal Teaching Hospital d'Abakaliki, capitale de l'État d'Ebonyi. Nigéria, mars 2023© Abba Adamu Musa/MSF
‘We are no longer afraid’: MSF hands over Lassa fever care in Ebonyi State
After seven years of critical support from MSF, local health authorities are now well equipped to take on Lassa fever with improved infrastructure, training, and resilience—saving lives and restoring confidence in the healthcare system.

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